Determinants of Telomere Length across Human Tissues - Paris Redox World Congress 2022 - June 22- 24, 2022


Determinants of Telomere Length across Human Tissues

parDr. Brandon L. Pierce, from The University of Chicago, USA will join the Paris Redox 2021 Congress which will be held on October 13-15, 2021 and will give a presentation entitled "Determinants of Telomere Length across Human Tissues".

Dr. Pierce explains that telomeres are DNA-protein complexes that protect chromosome ends. Their length is of great interest because short telomeres are associated with specific diseases and with aging. telomere length from 952 Genotype-Tissue Expression (GTEx) project donors across tissues, of which 24 tissue types have measurements for more than 25 samples. This dataset shows that telomere length is not constant but is correlated across tissues. Most tissue telomeres shorten with age, but some, such as those in the testis and cerebellum, do not. In African Americans, telomeres are longer on average than those from individuals of primarily European descent across many tissue types. This observation is consistent with variability being passed from germ cells to zygote to differentiated cells during development.

Paris Redox 2021 Congress
October 13-15, 2021 - Paris, France & Online

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